- Tretinoin for Beginners: A Guide to Getting Started
- Should You Choose Cream or Gel?
- Which Strength is Right for You?
- Tretinoin for Sensitive Skin: How to Use It Safely
- Tretinoin for Acne
- Tretinoin for Hyperpigmentation
- Tretinoin for Wrinkles and Fine Lines
- Tretinoin for General Skin Texture
- Tretinoin for Sun Damage
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Adapalene 0.1% Gel 15G
£21.99 Original price was: £21.99.£13.99Current price is: £13.99.
Acnelyse Tretinoin Cream 0.1% 20G EXP 11/28
Rated 5.00 out of 5 based on 17 customer ratings
(17 customer reviews)
£33.99
Description
Description
Product summary
Acnelyse 0.1% is a topical cream containing tretinoin, a prescription-only retinoid medicine in the UK. Each gram contains 1 mg of tretinoin (0.1%). The cream is supplied in a 20g tube and is manufactured by Abdi Ibrahim in Turkey. Current stock is marked EXP 11/2028 on the carton.
Tretinoin is used in the management of acne in appropriate patients. It can irritate the skin and is not suitable for every person or every skin concern. This product does not claim to remove acne scarring, reverse ageing, treat sunburn or provide a guaranteed result.
Store the tube as directed on its packaging. Keep it tightly closed, away from direct sunlight and heat, and out of the reach of children. Check the packaging for the expiry date before use. This listing concerns internationally manufactured stock. Tretinoin is prescription-only medicine in the UK, and customers are responsible for checking the rules that apply to their location, including any import requirements.
General directions and safety
These are general product-use considerations and do not replace advice from a prescriber or pharmacist. Follow the directions supplied with the product and any advice given by a qualified clinician.
- Cleanse gently and allow the skin to dry fully before application.
- Start gradually, such as on two or three non-consecutive nights per week, and increase only if your skin tolerates it and a clinician has advised that it is appropriate.
- Apply a thin layer using approximately a pea-sized amount for the whole face. Keep it away from the eyes, lips, nostril creases and broken, sunburned or irritated skin.
- Use a gentle moisturiser if needed to reduce dryness. Apply a broad-spectrum sunscreen during the day, because retinoids increase sun sensitivity.
- Do not apply more than directed. Avoid combining it with other potentially irritating treatments unless a clinician or pharmacist has advised this.
- Stop using it and seek medical advice if you develop severe, persistent or worsening irritation, swelling, blistering or a significant rash.
Who should speak to a clinician first
Speak to a doctor or pharmacist before using tretinoin if you are pregnant, planning a pregnancy or breastfeeding. Ask for advice first if you have eczema, rosacea, severe acne, markedly sensitive or damaged skin, or any condition affecting the intended treatment area. You should also seek professional advice if you are uncertain about your diagnosis, taking other topical or oral medicines, or have previously reacted to tretinoin or another retinoid.
Acnelyse strengths: 0.1% and 0.05% explained
Acnelyse is Abdi Ibrahim’s retinoic acid (tretinoin) cream. It is manufactured in two strengths: 0.1% and 0.05%. This listing is the 0.1% strength in the 20g tube, the stronger of the two. If you search for “Acnelyse 0.005%”, the strength you are looking for is usually labelled 0.05%; we currently stock the 0.1% version.
Comparing strengths across brands? See our full guide: where to buy tretinoin cream in the UK.
Frequently asked questions
What is Acnelyse 0.1% cream used for?
Acnelyse 0.1% contains tretinoin, a topical retinoid medicine used in the management of acne when clinically appropriate. It is not a general moisturiser or a treatment for every mark, rash or change in skin texture. A clinician or pharmacist can help establish whether acne is the correct diagnosis and whether this strength is suitable.
Is Acnelyce the same product as Acnelyse?
The spelling in that question is a variation used in searches, while this listing is for Acnelyse 0.1% cream. Check the tube, strength, active ingredient and manufacturer before use. The product described here contains tretinoin 0.1%, is supplied in a 20g tube, and is manufactured by Abdi Ibrahim in Turkey.
How should I start using Acnelyse 0.1%?
Introduce tretinoin gradually rather than applying it every night immediately. On dry, clean skin, use about a pea-sized amount for the whole face on two or three non-consecutive nights per week. Avoid the eyes, lips and damaged skin. Increase only if tolerated and consistent with advice from a clinician or pharmacist.
Is 0.1% suitable for first-time users?
0.1% is the higher of the two Acnelyse strengths. New users often begin with two or three nights per week and build up gradually as skin adjusts, and many prefer to start with a lower-strength tretinoin product first. Dryness and flaking in the first weeks are common. This is general product information, not medical advice: check with a pharmacist or doctor if you are unsure whether tretinoin is right for you.
Can Acnelyse 0.1% be used during pregnancy or breastfeeding?
Speak to a doctor or pharmacist before using tretinoin if you are pregnant, planning a pregnancy or breastfeeding. Do not make a personal decision based only on online product information. A clinician can consider your circumstances, explain relevant precautions and advise whether an alternative is more appropriate for your skin concern.
Is Acnelyse 0.1% available in the UK?
This retailer lists Acnelyse 0.1% for international sale and may offer delivery to UK addresses, subject to stock, destination and delivery terms. Tretinoin is prescription-only medicine in the UK. Customers should check current UK rules and any import requirements, and obtain professional advice about lawful and suitable use.
What should I do if tretinoin causes irritation?
Mild dryness, peeling or stinging can occur, particularly when tretinoin is introduced. Reduce use and seek advice if symptoms persist or worsen. Stop using the cream and obtain prompt medical advice for severe irritation, swelling, blistering or a significant rash. Keep it away from the eyes and do not apply it to broken skin.
What is the expiry date?
Current stock is marked EXP 11/2028 on the carton.
How is it delivered?
Orders ship from UK stock with tracked delivery.
Whilst we supply original manufactured products, the content displayed here is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Read labels, warnings and directions of all products before use.
Application method
Application method
Tretinoin Usage Guide for beginners:
Step 1: Start Low
- Begin with the 0.025% concentration, especially if you've never used Tretinoin or Retin-A before.
Step 2: Apply at Night
- Use Tretinoin as the final step in your nighttime routine.
- Apply a pea-sized amount to your face, avoiding:
- Corners of the nose
- Mouth
- Lips (as these areas are more sensitive).
Step 3: Protect Against Sun
- Tretinoin increases sun sensitivity. Always:
- Use a broad-spectrum SPF50 sunscreen during the day.
- Avoid prolonged sun exposure.
Step 4: Moisturize
- Combat dryness by:
- Using a hydrating moisturizer after Tretinoin or as part of your daytime routine.
Step 5: Consult & Educate
- Seek advice from a dermatologist or research proper usage and precautions before starting.
Would you like further assistance, like creating a routine or addressing specific skin concerns?
17 reviews for Acnelyse Tretinoin Cream 0.1% 20G EXP 11/28
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Rated 5.00 out of 5

Stephen O. (verified owner) –
Yet to use but previously great
Kerry C. (verified owner) –
Great product
Yulia (verified owner) –
I love this cream! I have acne prone sensitive skin.
Gayle (verified owner) –
Great new product!
Anonymous (verified owner) –
I was perfectly happy with the products I usually buy, but since there was an offer on for a new product, and it was recommended by the company (who I trust unreservedly) I thought I’d give it a go.
OMG, what can I say 🤷 Tretinoin World really do keep their finger on the pulse, and bring to us quality products at outstanding prices… This product is amazing!!!… Now I’ve found myself COMPLETELY spoilt for choice 😃
Love you Tretinoin World ♥️🥰
Ross B. (verified owner) –
Brilliant product, much less drying than the tretinoin gel
Wendy H. (verified owner) –
It’s really good to have this tretinoin in stock as it has a 2028 expiry date.
Anonymous (verified owner) –
Delivered on time and product as described.
Bernie (verified owner) –
Very happy with order but a bit more pricey than I normally pay. Very fast & efficient delivery. Had to pay €10 customs. But delighted to get it 😍
Sharon McCarthy (verified owner) –
Great anti-aging product. Gives a lovely glow.
Hannah (verified owner) –
Perfect
Anonymous (verified owner) –
Monika F (verified owner) –
Very good product and excellent quality. The delivery to the UK was extremely fast, and the customer service team was very helpful, responsive, and polite throughout the whole process. I am very satisfied with my purchase and would definitely order again. Highly recommended!
Sarah (verified owner) –
Amazing product, my skin is now flawless. The customer service is faultless, every question answered and in a timely manner, really friendly and postage is also super quick. Will definitely be a regular customer.
Emma Rice (verified owner) –
Great service as always !
Jenny (verified owner) –
Very pleased with the product can feel it working already, great service and quick delivery too!
Lesley (verified owner) –
Great service and product.. highly recommend