Hydroquinone

Hydroquinone creams

Hydroquinone is used to gradually lighten areas of excess pigment, such as melasma. This category lists Melalite Forte (hydroquinone 4%) and two combination creams that also contain tretinoin and a corticosteroid: Tri-Luma and Skin Light. They are not interchangeable.

Hydroquinone and tretinoin products differ in ingredients and use limits, so check each product page and the label on your pack. Both are prescription-only medicines in the UK, so speak to a pharmacist or doctor before use.

Single ingredient or combination

Melalite Forte contains hydroquinone alone. Tri-Luma and Skin Light add tretinoin and a steroid, in different strengths and with different steroids. A steroid on the face brings its own limits, so read each product page before comparing them.

Use limits

• The British Association of Dermatologists says hydroquinone may cause skin irritation and should only be used for a few weeks at a time, to prevent over-lightening.
• Hydroquinone may cause exogenous ochronosis, a gradual blue-black darkening of the skin. Stop and see a doctor if this happens.
• Sun exposure can darken treated skin again, so use a broad-spectrum sunscreen or protective clothing.
• Safety of hydroquinone in pregnancy has not been established.

Read our guides to hydroquinone for melasma and tretinoin and hydroquinone.